Molecular test for vivax malaria with loop-mediated isothermal amplification method in central China

Abstract Vivax malaria has the highest incidence in centralChina. High-throughput and cost-effective testing methodsare essential for vivax malaria diagnosis in this area. Loop-mediated isothermal amplification (LAMP) is an established nucleic acid amplification method, which provides a prom-ising platform for the molecular detection of malaria para-sites in development countries. This study was performed to compare the LAMP method, the nested PCR-based method,and microscopic examinations in diagnosing vivax malaria.